Science · 23 July 2026 · From issue 11

In mice, a new chemical hook locked onto target proteins without grabbing the wrong ones.

Zachary P. Shultz, Ansar Lee-Sam et al., Late-stage functionalization with strain-release warheads enables tunable covalent inhibition, Science.

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Also in issue 11 15 papers

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A new blood test method found over 1,200 new gene-protein links in South Asian volunteers.
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Invasive species do more damage in poorer nations, not richer ones as long assumed.
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Fast, not slow, nerve fibers drive the quick pull-away reflex from sharp pain.
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In a computer model, a painting's subject matches its art era better than its colors do.
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In a nearby galaxy, star clusters near giant bubbles form fewer heavy stars than clusters in spiral arms.
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In lab tests, recycled plastic cracked sooner and failed faster than new plastic under stress and chemicals.
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A ceramic foam kept its strength and shape above 2000 Kelvin in air.
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A new mapping method finds hidden stable and unstable shapes in connected springy systems.
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A computer model built from quantum physics predicted how liquids act when squeezed into tiny spaces.
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Eight copies of a bacterial enzyme must join into a ring to fight off viruses.
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In lab tests, a tiny metal additive stopped water from breaking down a heat-to-electricity material.
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