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PLOS Biology  ·  15 September 2026  ·  From issue 37

Does acute inflammation triggered by infection promote cancer progression?

In lab studies, common virus infections can help tumors grow and spread faster.

Felipe Valença-Pereira, Bryan Johnson et al.

Getting a common infection, like flu or COVID, might change how cancer grows inside the body. In lab studies, infections cause swelling and immune changes that can help tumors grow and spread. But the same immune response can sometimes attack cancer instead of helping it. Doctors do not yet know which effect wins in a real patient.

What it could change Common infections can push the body's defenses to either help or hurt a tumor.

Shows a lab-based link between infection-driven inflammation and cancer growth, not a proven human effect.

Lab and animal evidence only, not yet tested for real patients.

Integrity screen: passed (3 checks) Checked 22 September 2026. Retraction record: none. DOI resolves at doi.org. Metadata record found (PLOS Biology). Read the source

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