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Nature  ·  23 September 2026  ·  From issue 41

Lsp2 links early-life diet to adult translation and lifespan in Drosophila

In fruit flies, eating less protein as a baby made adults live longer.

Hina Kosakamoto, Rina Okada et al.

Baby fruit flies fed less protein grew up to live longer as adults. This happened because the young flies made less of a storage protein. That protein normally carries building blocks into adult cells. Cutting two specific amino acids in early life also lowered the storage protein and made the flies live longer.

What it could change A single storage protein in young flies controls how long they live as adults.

Shows one protein carries early diet effects into adult lifespan in flies only.

Fruit flies only, no human data yet.

Integrity screen: passed (3 checks) Checked 30 September 2026. Retraction record: none. DOI resolves at doi.org. Metadata record found (Nature). Read the source

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