Proceedings of the National Academy of Sciences · 5 October 2026 · From issue 47

A 2,623-year temperature reconstruction from the Colorado Rocky Mountains reveals warm and cool droughts

The worst drought in 2,000 years happened during a cool period, not a hot one.

Alexandre F. Nolin, Connie A. Woodhouse et al.

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Also in issue 47 15 papers

In adults, a brain activity pattern formed during fear learning predicted fear's return after brain stimulation therapy.
Nature Communications
In tumor samples, three gene changes and three immune types mark cervical cancer in Chinese patients.
PLOS Biology
Adding iron to electrodes made water break apart faster to clean pollutants.
Nature Communications
In mice, a new glowing dye found more hidden ovarian tumors than the current best dye.
Science Advances
A new computer program sorts cells and blood samples by disease status from raw protein data.
Nature Communications
A model using cause-and-effect chemical maps predicts toxic effects better than shape-only models.
Proceedings of the National Academy of Sciences
A dusty star disk swaps its bright and dark sides depending on the light used.
The Astrophysical Journal
In human gut cells, the same five gene wiring patterns repeat again and again during organ growth.
Proceedings of the National Academy of Sciences
In mice, a gut receptor switch controls fat absorption and gut inflammation in opposite directions.
eLife
In yeast cells, AI-picked antibody fragments blocked several snake toxins at once.
Science Advances
In diseased kidneys, lopsided gene copy use in the filtering unit linked to better outcomes.
Science Advances
Hard crystal pins between mineral layers let shellfish nacre stay stiff and resist cracking at once.
Science
Butterfly wing patterns team up with flapping flight to trick predators about their motion.
Nature
A new sulfur-based salt builds carbon triangle shapes more safely than old explosive methods.
Nature

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