Science · 3 September 2026 · From issue 31
Tumor-derived antioxidants suppress immunity by depriving T cells of reactive oxygen species
In mice, tumors release a substance that blocks T cells from attacking cancer.
Alexander J. Wesolowski, Ardon M. Pillay et al.
Tumors release a protective substance that soaks up reactive molecules T cells need to fight cancer. Without these molecules, T cells cannot turn on their attack signals. In mice, removing this substance from tumors let the immune system attack harder and made cancer treatment work better.
Shows a mechanism in mice, not a proven human treatment.
Mouse study only, no human safety or effectiveness data yet.
Integrity screen: passed (3 checks) Checked 10 September 2026. Retraction record: none. DOI resolves at doi.org. Metadata record found (Science). Read the source
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