Nature Communications · 8 August 2026 · From issue 19
In rodents, a tiny protein cage vaccine protected against two deadly Ebola virus types.
Connor Weidle, Natalie Brunette et al., Pan-Ebolavirus nanoparticle vaccine provides protection in rodents from lethal infection by Zaire and Sudan viruses, Nature Communications.
A lab-made protein shell shaped like two different Ebola viruses at once protected animals from deadly infection. Mice given a shot matched to one virus survived best. Guinea pigs given a mixed shot survived a related virus and made antibodies against both viruses. The mixed vaccine worked worse than a matched single-virus shot in mice, so results differed between species.
Shown only in mice and guinea pigs, not yet tested in humans.
Mice and guinea pigs only, no human data yet.
Integrity screen: passed (3 checks) Checked 11 August 2026. Retraction record: none. DOI resolves at doi.org. Metadata record found (Nature Communications). Read the source
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