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In this issue 15 papers · 5 free

01 Nature Diet at disease onset determines tissue inflammatory memory Free
02 Nature Communications Contrasting epigenetic dynamics in chromosome arms and pericentromeres during ROS1-induced plant immune memory Free
03 eLife Glutamate receptor composition at Drosophila neuromuscular junctions depends on developmental stage and muscle identity Free
04 eLife Fitness level, but not sex, affects exercise-induced pain modulation Free
05 Science Advances Dams not to blame for all reservoir carbon emissions from retained organic carbon Free
06 Nature Communications Excess type I interferon disrupts developmental crosstalk and promotes premature distalization in trisomy 21 lungs Subscribers
07 Monthly Notices of the Royal Astronomical Society A Multi-Wavelength Picture of the Surprisingly Short 2024/25 Outburst from EXO 0748-676 Subscribers
08 Nature Communications Process-dependent shifts in conspecific negative density dependence during boreal forest succession Subscribers
09 Proceedings of the National Academy of Sciences In-context learning as a retraining-free paradigm for constitutive modeling Subscribers
10 Proceedings of the National Academy of Sciences Where intention goes, responsibility flows: Grounding AI accountability in the machine learning paradigm Subscribers
11 Science Advances Monolithic and scalable capacitive electrodes leveraging parasitic capacitance for full-body pressure mapping Subscribers
12 Science Pervasive patterns in bird songs resemble those in human speech and song and are independent of vocal learning Subscribers
13 Physical Review Letters Consistent Time Reversal and Reliable and Accurate Inference in the Presence of Memory Subscribers
14 Proceedings of the National Academy of Sciences Mechanism of catalytic regulation by an allosteric hot spot in dihydrofolate reductase Subscribers
15 eLife Compensation of hyperexcitability with simulation-based inference Subscribers

The papers Read free

Nature·28 October 2026

Zewen Jiang, John M. Tayeri et al.

In mice, a short burst of fatty food at the start of skin inflammation makes it as severe as long term obesity.

A few days of fatty food at just the wrong moment can make skin disease much worse in mice, as bad as long term obesity does. Scientists found this only happens if the fatty diet hits during a short four day window right when skin inflammation starts. Fatty food calls white blood cells called neutrophils into the skin. These cells trigger an alarm system that fuels harmful immune cells, and this leaves a lasting mark even after the mice return to normal food.

The number 4-day window

The short time period when fatty food exposure worsened skin inflammation in mice.

Mice only, short time window tested, no human data yet.

Integrity screen: passed (3 checks) Checked 1 November 2026. Zewen Jiang, John M. Tayeri et al., Diet at disease onset determines tissue inflammatory memory Read the source

Nature Communications·31 October 2026

Adam Hannan Parker, Peijun Zhang et al.

In a lab plant, turning on a DNA-marking eraser built pathogen immune memory lasting one week.

A small flowering plant called Arabidopsis built immune memory after scientists briefly switched on a gene tool that removes chemical marks from its DNA. This memory helped the plant fight off disease-causing germs for at least one week. The marks changed in different ways across the plant's DNA. They loosened near defense genes but stayed locked in other spots tied to repetitive DNA.

The number 1 week

How long plant immune memory lasted after the DNA-marking eraser tool was briefly switched on.

Lab plant only, short one-week test, not a crop yet.

Integrity screen: passed (3 checks) Checked 1 November 2026. Adam Hannan Parker, Peijun Zhang et al., Contrasting epigenetic dynamics in chromosome arms and pericentromeres during ROS1-induced plant immune memory Read the source

eLife·30 October 2026

Anne Sustar, Chengjie Qiu et al.

Adult and baby fruit flies use different nerve-signal sensors at their muscle junctions.

Fruit flies use small sensors on their muscles to pick up signals from nerves. Baby flies and adult flies turn out to use different sets of these sensors at the junction where nerve meets muscle. Even muscles right next to each other in an adult leg use different sensor combinations. A separate sensor for the same signal chemical shows up only in adult muscle, not in young muscle.

What it could change Nerve-muscle sensor types change by body stage and even by which muscle they sit on.

Shows that fly muscles are not all wired the same way, challenging a common lab assumption.

Fruit flies only, lab study, no human or other-species data.

Integrity screen: passed (3 checks) Checked 1 November 2026. Anne Sustar, Chengjie Qiu et al., Glutamate receptor composition at Drosophila neuromuscular junctions depends on developmental stage and muscle identity Read the source

eLife·30 October 2026

Janne Ina Nold, Tahmine Fadai et al.

Fitness level, not sex, decides who feels less pain after hard exercise.

Hard exercise can dull pain more than easy exercise, but only for people who are very fit. In a study of 21 highly fit women, intense exercise lowered heat pain ratings more than light exercise, especially for the strongest pain test. When researchers combined this data with an earlier study, fitness level explained the pain relief, not sex.

The number 21 women studied

The number of highly fit women tested for pain relief after hard versus easy exercise.

Only 21 highly fit women tested, no men or low-fit women.

Integrity screen: passed (3 checks) Checked 1 November 2026. Janne Ina Nold, Tahmine Fadai et al., Fitness level, but not sex, affects exercise-induced pain modulation Read the source

Science Advances·30 October 2026

Wenqing Shi, Xiangyu Min et al.

In a global simulation, dams raise carbon emissions by just 21.5%, far less than past estimates.

Dams trap bits of dead plants and other organic matter, which rot and release carbon dioxide and methane. But that matter would still rot even without a dam, as it floated downstream or settled near the coast. A computer model of 5,346 dams compared each one to what would happen with no dam at all. Dams really do raise carbon emissions, but only by 21.5%, much less than older estimates claimed.

The number 21.5%

The average rise in carbon emissions caused by dams, once natural decay without a dam is subtracted.

Model only, covering 5,346 dams, not direct field measurements.

Integrity screen: passed (3 checks) Checked 1 November 2026. Wenqing Shi, Xiangyu Min et al., Dams not to blame for all reservoir carbon emissions from retained organic carbon Read the source

10 more papers are in the full issue.

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Nature Communications·1 November 2026

Randa Belgacemi, ChinYi Chu et al.