Nature Communications · 19 September 2026 · From issue 39
Extending single-cell proteomics from HeLa to small primary human immune cells
A single lab-grown cell can now reveal up to 7000 of its proteins at once.
Ivo A. Hendriks, Sara C. Buch-Larsen et al.
A new lab method can measure thousands of proteins in a single human cell. It works even on tiny immune cells taken straight from blood. The method found up to 7000 proteins in one lab-grown cell and up to 4000 proteins in single blood immune cells. This let scientists tell apart cell types like monocytes and T cells just from their protein patterns.
The number of distinct proteins measured inside a single lab-grown cell.
Lab cells and blood cells only, no patient disease data yet.
Integrity screen: passed (3 checks) Checked 22 September 2026. Retraction record: none. DOI resolves at doi.org. Metadata record found (Nature Communications). Read the source
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