Nature Communications · 27 October 2026 · From issue 58
Evaluation of vaccine-induced anti-lipopolysaccharide antibodies against clinically relevant Klebsiella pneumoniae strains to inform vaccine design
In lab tests, one antibody type killed most germ strains that cause newborn blood infections.
Robert Lawrence, Nathalie Karaky et al.
A vaccine ingredient can kill many strains of a dangerous newborn infection germ, a lab study shows. The germ, called Klebsiella pneumoniae, causes serious blood infections in babies and resists many antibiotics. Scientists tested antibodies made against one surface marker on 146 germ samples covering 17 different strains. Some strains died easily, some died sometimes, and some did not die at all, even though a different kind of antibody could still kill them.
The number of newborn-sepsis bacteria samples tested for antibody killing in this lab study.
Lab dish test only, no human or animal data yet.
Integrity screen: passed (3 checks) Checked 28 October 2026. Retraction record: none. DOI resolves at doi.org. Metadata record found (Nature Communications). Read the source
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