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In this issue 15 papers · 5 free

01 BMJ Reporting completeness of clinical trials evaluating large language model interventions in medicine: systematic review Free
02 Nature Communications Soil proteogenomics uncover microbial strategies for soil depth-specific carbon cycling under whole-soil warming conditions Free
03 Nature Communications CD200+ fibroblasts prime the immunoregulatory function of granulocytic myeloid-derived suppressor cells in inflammatory arthritis Free
04 Nature Communications Reinforcement learning guided robotic platform that investigates and discovers asymmetric reactions Free
05 The Astrophysical Journal Rapid Radio Variability in the z ∼ 7 Blazar VLASS J0410-0139: Indication of a Hidden Population of Weak Radio Jets at Cosmic Dawn Free
06 eLife Reduced dorsal CA1 activity limits retention of the temporal component of declarative memory in the Cntnap2 knockout mouse model of autism Subscribers
07 eLife Anatomy and mechanics of tsetse fly blood feeding Subscribers
08 eLife JAK-STAT pathway heterogeneity governs immunotherapy response in breast cancer Subscribers
09 Physical Review Letters Multipartite Mixed-Species Entanglement over a Quantum Network Subscribers
10 PNAS Nexus Viral capsid-membrane interactions propel non-brownian movements of non-enveloped reoviruses during entry Subscribers
11 Geophysical Research Letters Decadal Sea Level Variability Along the U.S. East Coast: Roles of Extratropical Versus Tropical Climate Modes Over the North Atlantic Ocean Subscribers
12 Proceedings of the National Academy of Sciences Improved assessment of Alaskan Arctic coastal wave exposure accounting for landfast ice Subscribers
13 Proceedings of the National Academy of Sciences Multidimensional vulnerabilities of informal settlements in the Urban South Subscribers
14 Proceedings of the National Academy of Sciences Laundering and evasion in response to antislavery policies in Brazil’s cattle sector Subscribers
15 Science Asymmetric enzymatic hydrophosphorylation through O 2 activation Subscribers

The papers Read free

BMJ·13 October 2026

David Chen, Ayden Blayne et al.

Clinical trials of AI chatbots often fail to report key safety and method details.

Many medical studies testing chatbot style AI tools leave out key details. A review of 68 trial reports, 15 study plans, and 378 trial listings found this gap. Reports often skipped facts about how the tool was built and tested. They also left out details on possible harms and how the tool was watched for problems.

The number 40% to 61%

average reporting completeness scores across trial reports, protocols, and registrations for AI tool trials in medicine

Review of 68 published trials only, not a test of safety.

Integrity screen: passed (3 checks) Checked 30 October 2026. David Chen, Ayden Blayne et al., Reporting completeness of clinical trials evaluating large language model interventions in medicine: systematic review Read the source

Nature Communications·13 October 2026

Ulas Karaoz, Ricardo J. E. Alves et al.

Soil depth, not warming, mainly decided which food sources soil microbes used to break down carbon.

Soil holds more carbon than the air and all plants combined. Scientists still do not fully know how tiny soil microbes break that carbon down, especially deep underground. A seven and a half year experiment warmed soil by 4 degrees Celsius, from the surface down to 90 centimeters. It tracked which microbe skills showed up at each depth. Surface microbes mostly ate a simple gas called methanol. Deep microbes relied on fermentation, carbon monoxide, and capturing nitrogen from the air. Warming changed these patterns, but the changes were smaller over time and different at each depth.

The number 4 degrees Celsius warming over 7.5 years, down to 90 centimeters deep

The size and depth of the soil warming experiment that revealed these microbial changes.

One long-term soil warming experiment, not yet tied to real-world climate outcomes.

Integrity screen: passed (3 checks) Checked 14 October 2026. Ulas Karaoz, Ricardo J. E. Alves et al., Soil proteogenomics uncover microbial strategies for soil depth-specific carbon cycling under whole-soil warming conditions Read the source

Nature Communications·13 October 2026

Mario R. Angeli, Christian Schütz et al.

In mice, joint lining cells train immune cells to calm inflammation, and blocking this made arthritis worse.

Certain immune cells can calm down joint inflammation, but only inside the joint itself, not in the blood. Cells in the joint lining send signals that turn young immune cells into these calming cells. In mice with arthritis, blocking that signal stopped the calming cells from forming. This made the disease worse.

What it could change Blocking one joint signal stopped calming immune cells from forming and made arthritis worse in mice.

Shows a joint tissue signal that helps control inflammation in mice with arthritis.

Mouse and cell studies only, no human trial yet.

Integrity screen: passed (3 checks) Checked 14 October 2026. Mario R. Angeli, Christian Schütz et al., CD200+ fibroblasts prime the immunoregulatory function of granulocytic myeloid-derived suppressor cells in inflammatory arthritis Read the source

Nature Communications·13 October 2026

Patryk Klochowicz, Ahmad F. Kassir et al.

In lab tests, a robot using trial-and-error learning found four new mirror-shaped chemical reactions on its own.

A robot chemist worked for 30 days without a human guiding each step. It made over 3,000 decisions on its own and found four new chemical reactions. These reactions build molecules with a special mirror-image shape. That shape matters a lot in medicine design.

The number 3,000+ decisions in 30 days

The number of choices the robot made while searching for new mirror-shaped reactions.

Lab-only test with one acid helper, not yet broadly proven.

Integrity screen: passed (3 checks) Checked 14 October 2026. Patryk Klochowicz, Ahmad F. Kassir et al., Reinforcement learning guided robotic platform that investigates and discovers asymmetric reactions Read the source

The Astrophysical Journal·13 October 2026

Silvia Belladitta, Eduardo Bañados et al.

A far away young galaxy's radio light flickered fast because a narrow jet points almost at Earth.

A distant galaxy, seen as it looked less than a billion years after the universe began, has a beam of fast particles pointed almost straight at Earth. This beam makes its radio light flicker brightly in just months. The beam is weak on its own, but points at us so closely that it looks bright. This hints that many more hidden galaxies like it exist, with similar beams we cannot see because they point elsewhere.

The number less than 3 degrees

How closely the galaxy's jet of fast particles points toward Earth, based on radio brightness changes.

One distant galaxy studied, few observation rounds, no broader sample yet.

Integrity screen: passed (3 checks) Checked 14 October 2026. Silvia Belladitta, Eduardo Bañados et al., Rapid Radio Variability in the z ∼ 7 Blazar VLASS J0410-0139: Indication of a Hidden Population of Weak Radio Jets at Cosmic Dawn Read the source

10 more papers are in the full issue.

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eLife·13 October 2026

Elise Caitlin Rawlinson, Michael Hugh McCullough et al.