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In this issue 15 papers · 5 free

01 PLOS Medicine Effect of food swap recommendations on the healthfulness and carbon footprint of grocery purchases in a naturalistic online store: A randomized parallel trial Free
02 Science Advances Modeling the effects of climate risk on primates globally: New perspectives on conservation priorities Free
03 eLife Multiple molecular pathways to longevity with opposing gene expression programs defining distinct aging strategies in Caenorhabditis elegans Free
04 Nature Communications Enhanced axonal mitochondrial motility and neural activity-induced energy deficits destabilize synaptic transmission in models of bipolar disorder Free
05 Nature Communications Soft microgel networks stabilize and extend nozzle-free water jets Free
06 Nature Communications Longitudinal digital phenotyping of activity rhythms and biological aging using commercial wearables Subscribers
07 Monthly Notices of the Royal Astronomical Society Amplifying the imaging power of digital sky surveys with space telescopes data and generative AI Subscribers
08 Nature Medicine Responsiveness of epigenetic aging biomarkers to longevity interventions in humans Subscribers
09 Science Genomes of Poaceae relatives reveal key metabolic innovations preceding the evolution of grasses Subscribers
10 Physical Review Letters Toward First Detection of the Solar Mikheyev-Smirnov-Wolfenstein Transition with JUNO Subscribers
11 Proceedings of the National Academy of Sciences Advances in small area population estimation in the absence of national census data Subscribers
12 Proceedings of the National Academy of Sciences YBX1 regulates RNA polymerase III transcripts to prevent inflammation Subscribers
13 Proceedings of the National Academy of Sciences Profile of C. Robin Buell Subscribers
14 Science Advances δ2-Protocadherins organize parallel indirect basal ganglia circuits Subscribers
15 Science Advances Photocatalytic CO 2 -to-ethanol conversion via multiple enrichment effects in porous liquids Subscribers

The papers Read free

PLOS Medicine·21 August 2026

Anna H. Grummon, Kevin O’Sullivan et al.

Grocery swap suggestions made online shopping carts healthier or lower carbon, depending on the suggestion type.

Pop-up suggestions for swapping groceries changed what people put in their online shopping carts. Suggesting greener food swaps lowered the carbon footprint of carts. Suggesting healthier swaps made carts more nutritious. Mixing both types of suggestions helped both goals a little, but did not beat single-focus suggestions at either one.

The number 4.7 point increase in healthfulness score (out of 100)

The improvement in grocery cart healthfulness when shoppers saw health-focused swap suggestions, compared to no suggestions.

1,201 US adults, online simulated store only, not real shopping.

Integrity screen: passed (3 checks) Checked 23 August 2026. Anna H. Grummon, Kevin O’Sullivan et al., Effect of food swap recommendations on the healthfulness and carbon footprint of grocery purchases in a naturalistic online store: A randomized parallel trial Read the source

Science Advances·21 August 2026

Yang Teng, Yueqi Yin et al.

In a model, tropical American and south China primates face the highest future climate risk.

Primate groups in tropical parts of the Americas and in southern China face the biggest risk from future climate change. A computer model followed 424 primate species using their family trees. It found these regions hold younger species groups with less evolutionary variety, plus heavy human pressure and few protected areas.

The number 424 primate species

The number of primate species whose family tree and climate risk were mapped worldwide.

Model only, covers 424 species, no field testing of outcomes.

Integrity screen: passed (3 checks) Checked 23 August 2026. Yang Teng, Yueqi Yin et al., Modeling the effects of climate risk on primates globally: New perspectives on conservation priorities Read the source

eLife·20 August 2026

Zenith D Rudich, Jiaxi Guan et al.

In worms, many different long-life tricks turn on the same set of genes.

Long-lived worms of many different types switch on many of the same genes. Nine kinds of roundworms lived longer through seven different biological tricks, yet they often turned the same gene sets up or down. Some worms split into two camps that flipped the same genes in opposite directions, showing there is more than one way to live longer. Turning on some of these shared genes alone let ordinary worms live longer and handle stress better.

The number 196 genes up, 62 genes down

Genes that changed the same way in at least 6 of 9 long-lived worm strains.

Roundworms only, lab study, no human data yet.

Integrity screen: passed (3 checks) Checked 23 August 2026. Zenith D Rudich, Jiaxi Guan et al., Multiple molecular pathways to longevity with opposing gene expression programs defining distinct aging strategies in Caenorhabditis elegans Read the source

Nature Communications·22 August 2026

Sunan Li, Gui-Jing Xiong et al.

In lab-grown human brain cells and mice, restless energy factories inside brain cells destabilize signals linked to bipolar disorder.

Brain cells grown from bipolar disorder patients cannot hold their tiny energy factories in place. These energy factories, called mitochondria, normally sit at the spots where brain cells send signals to each other. In bipolar cells, they move around too much and leave those spots empty, which drains energy and makes signals unpredictable. A drug called lithium fixed this problem in the lab and also fixed manic-like behavior in mice.

What it could change A cellular reason lithium may help calm bipolar disorder symptoms was uncovered in lab models.

Shown only in lab-grown neurons and mice, not yet confirmed in patients.

Lab-grown cells and mice only, not tested in real patients.

Integrity screen: passed (3 checks) Checked 23 August 2026. Sunan Li, Gui-Jing Xiong et al., Enhanced axonal mitochondrial motility and neural activity-induced energy deficits destabilize synaptic transmission in models of bipolar disorder Read the source

Nature Communications·22 August 2026

Atieh Razavi, Mehrzad Roudini et al.

Soft gel particles stretched sound-driven water jets up to 44% longer before breaking.

Adding tiny soft gel particles to water can make a fast, thin jet of liquid stretch much farther before it breaks apart. These particles link together at the water's surface into a stretchy web. The web holds the jet together longer. Softer particles kept this web intact. Stiffer particles broke apart under stress, so the jet snapped sooner. Computer models showed the soft particles form tangled bridges. These bridges lower the water's surface tension and let it stretch more.

The number 44%

The increase in jet length when soft gel particles were added to the water.

Lab and simulation only, no real device tested yet.

Integrity screen: passed (3 checks) Checked 23 August 2026. Atieh Razavi, Mehrzad Roudini et al., Soft microgel networks stabilize and extend nozzle-free water jets Read the source

10 more papers are in the full issue.

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Nature Communications·22 August 2026

Jinjoo Shim, Jukka-Pekka Onnela